A powerful natural alternative to metformin or lipitor when treating diabetes
Cluster Fig Trees are commonly known and used in India, Bangladesh, Australia, Taiwan, Hainan and many parts of Asia. Here’s a few common names:
- United States Cluster Fig Tree
- India Gular tree
- South India Athi tree
- In Sanskript Udumbara
Botanic name: Ficus racemosa or Ficus glomerata belonging to the Moraceae family. A medium size tree, producing round fruits resembling an oval shaped fig. The figs have a red-brown color and grow out of the tree trunk. The fruits are a favorite staple of the common Indian macaque. This tree is sacred in India.
#1 ANTI DIABETES
Extracts from Cluster Fig Tree dramatically lowers blood sugar and increase insulin production even when pancreas beta cells have been damaged. This is an indication of strong anti diabetic compounds.
The extract made from stem bark has the most blood sugar lowering properties. In one study using oral administration of cluster fig tree extract 400 mg/kg showed a significant decrease in glucose levels at the end of 21 days.
The use of alcohol bark extract of Ficus racemosa significantly reduced the blood sugar level (80%) and restored the status of lipids and lipoproteins (60-70%) to near normal range. The present study also warrants further studies to isolate and characterizing potent molecules for diabetes mellitus and its lipids associated complications.
The hypoglycemic effect of Ficus racemosa still need more study. Blood sugar lowering is mostly done by an increase in production of insulin created by the plant’s compounds by the pancreatic cells that still healthy. Scientific data
#2 CHOLESTEROL LOWERING
Both stem bark and fruit has anti cholesterol properties. One study evaluating the anti diabetic and anti cholesterol properties of cluster fig had promising results. It concluded that after 45 days of administration of alcohol extract from the bark, laboratory mice were noted to have marked decrease in cholesterol levels.
#3 ANTI BACTERIAL & ANTI FUNGAL
Cluster fig has been used externally to treat skin diseases for thousands of years when chemical based medications were not available. The bark extract of cluster fig tree contains the largest amount of anti bacterial properties. Several studies found the bark extract to fight gram negative and gram positive bacteria. Also the high concentration of antioxidants function as a protection from infections.
#4 WOUND HEALING
Wound healing starts from the moment of injury and can continue for varying periods of time depending on the extent and wound size. Healing process can be categorized into three stages 1. inflammatory phase, 2. proliferative phase and finally the 3. remodeling phase which ultimately determines the strength and appearance of the healed tissue. In the results of the present study, complete wound healing activity was found to be maximum 84.36% on day 17 when treated with mupirocin 5% ointment. Similarly, complete wound healing activity was found 81.30% on day 18th, by applying ethanolic extract of Ficus racemosa as compared to the control group not using any agent 62.22% on day 24th.
Ficus recemosa or cluster fig tree extract have been for many years, the best remedy to treat diarrhea or disenteria. The decoction of bark skin is extremely useful in diarrhea, dysentery and ulcerative colitis. Ethanol extract of stem bark has shown significant inhibitory activity against castor oil induced diarrhea and PEG2 induced enteropooling in rats and also showed a significant reduction in gastro intestinal motility in charcoal meal test in rats which proves its efficacy as antidiarrheal. (see study)
#6 ANTI INFLAMMATORY / ANALGESIC
Cluster fig tree posses powerful anti inflammatory properties. The bark extracts can be used externally to treat skin inflammatory problems. The presence of biologically active principles such as flavonoids, tannins, phenolic compounds and phytosterols in the same plant from Phytochemical investigation suggests that one of above constituent or in combination together is responsible for producing the analgesic and anti- inflammatory effects. See study
#7 LIVER PROTECTION
Methanol extract of Ficus racemosa stem bark were studied using the model of hepatotoxicity induced by carbon tetrachloride (CCl4) in rats. CCl4 administration induced a significant increase in total bilirubin associated with a marked elevation in the activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) as compared to control rats. Pretreatment with methanol extract resulted in significant decreases in the activities of AST, ALT and ALP, compared to CCl4-treated rats. The results indicate
#8 ANTI ULCER
A antiulcer study was done using 100, 200 and 400 mg/kg of ethanolic extract of Ficus racemosa Linn. The extract was applied to different gastric ulcer models like Pylorus ligation, aspirin and ethanol induced gastric ulcer. The ethanolic extract was administered orally to various groups. Ulcer were scored and analyzed as described earlier. The result indicated a dose- dependent antiulcerogenic activity in ethanolic extract of Ficus racemosa Linn. (Tables 1, 2 and 3). The optimal effect was observed at the dose of 400 mg/kg body weight. (see study)
#9 ANTI FEVER
Analgesic and Anti Pyretic Properties: The bark extract has both fever reducing and pain relieving property, a cup of the water decoction of the cluster fig bark will greatly relieve pain and inflammation. They also relieve one of burning sensation.
#10 RENAL ANTICARCINOGENIC
Ficus racemosa extract at a dose of 200 and 400 mg/kg when given orally a significant decrease in lipid peroxidation, xanthine oxidase, γ-glutamyl transpeptidase and hydrogen peroxide (H2O2) generation with reduction in renal glutathione content and antioxidant enzymes generated by Potassium bromate (KBrO3), a potent nephrotoxic agent that induces renal carcinogenesis in rats. There was significant recovery of renal glutathione content and antioxidant enzymes. There was also reversal in the enhancement of renal ornithine decarboxylase activity, DNA synthesis, blood urea nitrogen and serum creatinine26. This result suggests that Ficus racemosa extract is a potent chemopreventive agent and suppresses KBrO3-mediated nephrotoxicity in rats.
A ancient healing plant
This plant has several therapeutic uses in the traditional system. All parts of the plant are involved in medicinal cure. Leaves tend to cure bilious infections. Fruits are known to counter constipation and diarrhea. Bark of the plant cures dysentery, spongy gums, ulcers, diabetes, asthma, leucorrhea and urinary problems. With its traditional uses, Udumbara has many biological properties like antitussive, chemo preventive, hepatoprotective, anti-inflammatory, antidiuretic and antipyretic.
Parts of the plant contain several phytochemicals which are responsible for fighting disease. Roots of the plant contain euphorbol and its hexacosanoate, tinyatoxin, cycloartenol and taraxerone. Bark consists of elements like taraxerone, leucoanthocyanins such as leucocyanidin-3- O-β-glucopyranoside and leucopelarogonidin-3-O-α-Lrhamnopyranoside, euphorbol and its hexacosanate, β-sitosterol, ingenol, stigma sterol, lupeol, unidentified long chain ketone and ceryl behenate.
Leaves of the plant contain glauanol acetate racemosic acid Tetra triterpene. Fruit consists lupeolacetate, β sitosterol, glauanol, higher hydrocarbons, glucose, hentriacontane, tiglic acid, phytosterol, esters of taraxasterol and friedelin. Latex of the tree contains euphol, a-amyrin, trimethyl, ellagic acid, tirucallol, euphorbinol, isoeuphorbol, tinyatoxin, taraxerol, cycloartenol, β-sitosterol 4-deoxyphorbol and palmitic acid.
Many modern diseases such as diabetes, obesity and fatty liver are suspected to be caused by a shift in balance between pro-oxidant and antioxidants in the body (1). Reactive oxygen species (ROS), commonly known as antioxidants are well documented as being the cause of many toxicities in the body.
These ROS differ significantly in their interactions and can cause extensive cellular damage such as nucleic acid strand scission (2), modification of polypeptides, lipid peroxidation etc. (3). Ionizing radiation also generates ROS causing non- selective damage to both tumor and normal cells. Therefore development of selective free radical scavengers which could protect normal cells during radiotherapy is an important strategy in radioprotector drug development. Several members of the genNutritional Value of Cluster Fig Fruit
Nutritional value of Cluster fig
|Total carbohydrate||15.84 gm|
|Ascorbic acid||5.3 mg|
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- HYPOLIPIDEMIC ACTIVITIES OF FICUS RACEMOSA LINN. BARK IN ALLOXAN INDUCED DIABETIC RATS
- Ficus racemosa Stem Bark Extract: A Potent Antioxidant and a Probable Natural Radioprotector
- EVALUATION OF THE ANTIOXIDANT ACTIVITY OF FICUS RACEMOSA PLANT EXTRACTS FROM NORTH-WESTERN DISTRICT OF BANGLADESH
- Antinociceptive activity of the ethanolic extract of Ficus racemosa Lin. (Moraceae)
- Antidiabetic Potential of Alcoholic and Aqueous Extracts of Ficus racemosa Linn. Bark In Normal and Alloxan Induced Diabetic Rats
- Anthelmintic activity of the crude extracts of Ficus racemosa
- Glucose-lowering, Hepatoprotective and Hypolipidemic Activities of Stem Bark of Ficus racemosa in Streptozotocin-Induced Diabetic Rats
- Ficus racemosa Linn. – An overview
- Antioxidant activities of ficus glomerata (moraceae) leaf gall extracts.
- Antioxidant Properties of Ficus Species – A Review
- Bioactive components from Ficus glomerata
- BERGENIN ISOLATED FROM FICUS GLOMERATA BARK
- Anti – HIV-1 integrase activity of Thai Medicinal Plants
- Effect of Ficus racemosa stem bark on the activities of carbohydrate hydrolyzing enzymes: An in vitro study
- Antimicrobial activities and phytochemical composition of extracts of Ficus species: An over view
- Effects of Plant Extracts on HIV-1 Protease
- PHYTOPHARMACOLOGICAL PROPERTIES OF FICCUS RACEMOSA LINN – AN OVERVIEW
- EXPERIMENTAL EVALUATION OF FICUS RECEMOSA LINN. FRUITS EXTRACT ON GASTRIC ULCERATION