Metabolic Syndrome is the modern disease – diabetes is one of it’s ramifications
- high lipid profile
- cardiovascular disease
- Metabolic syndrome starts in your liver. As the liver accumulates fat due to excess glucose intake and can’t be processed fast enough; the liver becomes insulin resistant. A fatty liver leads to a cascade of events which damage every organ in the body.
- As the liver becomes insulin resistant it begins to malfunction in its most important function – the transport of energy. The pancreas sensing this begins to produce more insulin. This added insulin surge only makes matters worse causing more fat to be stored in the liver and creating more insulin resistance leading to obesity.
- The liver tries to get rid of the fat by transporting it to subcutaneous tissue thus flooding the blood with lipids (fat in the blood) increasing the risk for heart disease.
- The excess insulin now in the system causes smooth muscles cells that surround the blood vessels to grow abnormally fast causing constriction thus leading to high blood pressure (so glucose over consumption has something to do with high blood pressure)
- The combination of insulin resistance, fatty liver and high blood pressure causes many problems and lead to cardiovascular disease and risk of heath attack and stroke.
- Fatty liver disease can progress to cirrhosis
- As the pancreas goes ballistic producing more and more insulin to compensate for insulin resistance by the liver it risks having a total failure from the β cells thus leading to diabetes type II
- Hyperinsulinemia is a condition associated with the growth of various cancers
- First it uses some of that energy for its own functioning needs
- Second when the energy entering the liver is glucose the liver turns excess glucose into glycogen which is then available to be used as stored energy and when you are not eating
- Third the liver has to deal with the excess of glucose ingested such as table sugar, alcohol, high fructose corn syrup. This extra energy is processed into fat and if it fails it can get very sick very fast
- Trans fats
- Can’t be broken down in the mitochondria because they are a synthetic product. They have been long associated with metabolic disease and the hardening of the arteries. Recently they have become less popular and the media has helped to reveal its true character but trans fat still being found in many industrialized foods, candies and baked goods making children especially vulnerable
- Branched-chain amino acids
- We can’t make them so we eat them and they are abundantly found in corn food stuffs, so every time you eat beef of pork you are ingesting them. They are not bad for you if you need them or can process them. Body builders consume them in great quantities in their protein shakes but because if you are building muscle it is being processed posing no harm. If you don’t need them because you don’t perform heavy work that require strength branched-chain amino acids are processed as fat
- In small doses it can be good for you and doctors recommend a couple of glasses of wine at the dinner table. Alcohol has been clearly associated with metabolic syndrome when consumed in great amounts especially if the alcohol contains sugars. Alcohol goes to the mitochondria without stopping at glycogen creating more ROS.
- Probably the worst of all three. Fructose consumption is growing all around the globe and nothing seems to be able to stop it. Sugar is added to 80% of package foods under different names so you don’t even know if the food you buy has sugar. Children eat fructose at an alarming rate. There is a clear correlation and causation to metabolic syndrome and the consumption of glucose.
Metabolic Syndrome by Dr Robert H. Lustig
Watch the 7 part series video documentary
The Skinny on Obesity
Metabolic Syndrome Journals
- Increasing Prevalence of the Metabolic Syndrome Among U.S. Adults
- JCI -Increased oxidative stress in obesity and its impact on metabolic syndrome
- 0742-3071 Blackwell Publishing, 2006 23Special Report Special report Metabolic syndrome K. G. M.
- Cardiovascular Morbidity and Mortality Associated With the Metabolic Syndrome
- JAMA Network | JAMA | Prevalence of the Metabolic Syndrome Among US Adults: Findings From the Third
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